{"id":158,"date":"2014-06-18T15:43:30","date_gmt":"2014-06-18T15:43:30","guid":{"rendered":"http:\/\/wpdev.acsu.buffalo.edu\/wnygirp\/?page_id=158"},"modified":"2019-04-25T16:48:01","modified_gmt":"2019-04-25T16:48:01","slug":"project-details","status":"publish","type":"page","link":"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/project-details\/","title":{"rendered":"Project Details"},"content":{"rendered":"<div class=\"wider\">\n<div>The innovative technology experience for students and teachers used in this project\u00a0involves a \u201chands-on\u201d cyber-learning approach, known as <a href=\"http:\/\/www.geni-act.com\/\">GENI-ACT<\/a>, that will involve participants in a current and global research project while learning basic concepts of biology.<\/div>\n<div><\/div>\n<p>The GENI-ACT \u00a0is a package \u00a0of nine independent modules that will allow students and teachers to annotate a gene from a bacterium. \u00a0Annotation is the process of assigning biologic function to to a gene. \u00a0The 9 modules of GENI-ACT and their purpose are shown in the figure below:<\/p>\n<figure id=\"attachment_414\" aria-describedby=\"caption-attachment-414\" style=\"width: 300px\" class=\"wp-caption alignnone\"><a href=\"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-content\/uploads\/sites\/25\/2015\/04\/Module_Description.png\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-414 size-medium\" src=\"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-content\/uploads\/sites\/25\/2015\/04\/Module_Description-300x280.png\" alt=\"Module_Description\" width=\"300\" height=\"280\" srcset=\"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-content\/uploads\/sites\/25\/2015\/04\/Module_Description-300x280.png 300w, http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-content\/uploads\/sites\/25\/2015\/04\/Module_Description.png 774w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><figcaption id=\"caption-attachment-414\" class=\"wp-caption-text\">The 9 Modules of GENI-ACT. The tools used in each module and the answers each module are meant to answer are shown. Click on the image to see a larger version.<\/figcaption><\/figure>\n<div><\/div>\n<div>Use of the modules encourages participants to:<\/div>\n<div><\/div>\n<div>\n<ul>\n<li style=\"list-style-type: none\">\n<ul>\n<li style=\"list-style-type: none\">\n<ul>\n<li style=\"text-align: left\">Use and master multiple database analysis software packages related to <a href=\"http:\/\/en.wikipedia.org\/wiki\/Bioinformatics\" rel=\"nofollow\"><span style=\"color: #0000ff\">bioinformatics<\/span><\/a>.<\/li>\n<li style=\"text-align: left\">Strengthen library and web-search skills<\/li>\n<li style=\"text-align: left\">Develop skills in making hypotheses and the design of experiments to test them<\/li>\n<li style=\"text-align: left\">Sharpen skills in analysis, synthesis and in the presentation and interpretation of results<\/li>\n<li style=\"text-align: left\">Experience the collaborative nature of science.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>See how gene annotation demonstrates the use of the <a href=\"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-content\/uploads\/sites\/25\/2019\/04\/Scientific_Method_geni-act.png\">scientific method.<\/a><\/p>\n<p><strong>The project\u00a0will target teacher populations as follows:<\/strong><\/p>\n<\/div>\n<\/div>\n<div class=\"wider\"><\/div>\n<div class=\"wider\">(i) the project focuses \u00a0on educators of rural groups of students currently underrepresented in biomedical sciences, within counties primarily served by <a href=\"http:\/\/www.r-ahec.org\">R-AHEC<\/a>\u00a0during its first year,\u00a0\u00a0including the Rochester NY Public School system, as well as \u00a0educators of underrepresented students in urban and suburban\u00a0school districts of Erie and Niagara counties served by <a href=\"http:\/\/enahec.org\">EN-AHEC<\/a><\/div>\n<div class=\"wider\"><\/div>\n<div class=\"wider\">(ii) the project\u00a0will offer a select subset of enthusiastic teachers from each year the opportunity to continue for a second year to further hone their annotation skills and become \u201cMaster Annotation Teachers\u201d. This additional level of training will allow this cohort of teachers to acquire a master level of proficiency that they can then utilize as ambassadors for the SEPA project, and aid in the recruiting, training and technical support of other educators.<\/div>\n<div class=\"wider\"><\/div>\n<div class=\"wider\">\n<p><strong>The project is broken down into three main components:<\/strong><\/p>\n<p><strong>Summer Teacher Training Workshop:<\/strong><\/p>\n<p>A\u00a0summer training workshop for teachers who will subsequently guide their students to perform basic gene annotations later in the project will take place in July. \u00a0\u00a0Teachers will have a clinical focus to their training, by (i) receiving \u00a0training in biomedical applications of bioinformatics during their summer training, and (ii) focusing on genes of clinical significance in human microbial pathogens (e.g. virulence genes, antibiotic resistance genes). The significance of annotation to novel gene discovery, to anchoring of metagenomic sequencing data and to the accuracy of gene calling from such a unique organism will be\u00a0stressed. Experts in clinical bioinformatics or molecular diagnostic fields will participate in the teacher training workshop. \u00a0The summer training workshop for teachers will\u00a0have 5 continuous days of training in one week over the summer. \u00a0Teachers will then come\u00a0back to UB for the equivalent of 2 refresher training days in the fall to refresh their gene annotation skills prior to having them work with their students for the semester 2 gene annotation and then for another day in the spring to help them with the review of their students\u2019 progress and to help them prepare for the final capstone poster presentations. Teachers still have a total of 8 days of training in the project and be paid for their time in training and in working with their students.<\/p>\n<p><strong>Semester 1 Activities:<\/strong><\/p>\n<p>The Semester 1 activities for the SEPA project will build student knowledge in the areas of molecular diagnostics and clinical genomics. We envision\u00a05 activity modules to achieve this goal:<\/p>\n<ol>\n<li><strong>Activity 1<\/strong>: \u201cSpotlight on Health Professionals and Genomics\u201d including videos of interviews with those individuals discussing how and why they entered the field.\u00a0 Students will be offered career guidance by AHEC facilitators at the end of this activity as well.<\/li>\n<li><strong>Activity 2: \u201c<\/strong>Building a Company Role Play\u201d as a group, students will explore the different types of positions necessary to build a successful bioscience company. This activity is meant to expose students to the variety of career opportunities in STEM fields.<\/li>\n<li><strong>Activity 3:\u00a0 <\/strong>SEPA Project Overview Presentation by Dr. Stephen Koury or Dr. Rama Dey-Rao is designed to introduce your students to the work they would be completing during the school year if selected as part of the treatment group. Dr. Koury and Dr. Dey-Rao review the nine modules in GENI-ACT and answer student questions.<\/li>\n<\/ol>\n<p><strong>Semester 2 Gene Annotation:<\/strong><\/p>\n<p>The project\u00a0will involve gene annotation of prokaryotes. The organization of genes is simpler in prokaryotes and the complications of alternative splicing are avoided. Annotations of prokaryotic genes are therefore likely to be more easily grasped by high school level students.<\/p>\n<p>The project will use genomes of multiple clinically significant microorganisms in Genbank as subjects for the annotation activities. These will be chosen to complement discussions in Semester 1 and will involve students doing research to generate background information about the organism, the types of infection it causes, the outcomes that result from infection and whether molecular diagnostic tests exist for their organism. Each school will be assigned a different organism on which to work. A mixture of genes will be selected from each organism for the students to annotate.<\/p>\n<\/div>\n<p>Examples of work on the genome annotation project performed by high school students and MS level students at the university at Buffalo can be seen in the <span style=\"color: #0000ff\"><a href=\"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/student-research\/\">Student Research<\/a><\/span>\u00a0page of this website.<\/p>\n<p><strong>Interested in participating?<\/strong><\/p>\n<p>Please see the official <a href=\"https:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-content\/uploads\/sites\/25\/2015\/04\/SEPA-Packet-2015_NYS-AHEC-Version.pdf\">program recruitment flyer<\/a> and contact the coordinator of the project in the AHEC representing your school district on\u00a0the <a title=\"Contact Information\" href=\"http:\/\/wpdev.acsu.buffalo.edu\/wnygirahcp\/contact-information\/\">Contact Information Page.<\/a><\/p>\n<div>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<div class=\"wider\">\n<div><\/div>\n<div><\/div>\n<p>&nbsp;<\/p>\n<div><\/div>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The innovative technology experience for students and teachers used in this project\u00a0involves a \u201chands-on\u201d cyber-learning approach, known as GENI-ACT, that will involve participants in a current and global research project &hellip; <a href=\"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/project-details\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Project Details<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":12,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"class_list":["post-158","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-json\/wp\/v2\/pages\/158","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-json\/wp\/v2\/comments?post=158"}],"version-history":[{"count":6,"href":"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-json\/wp\/v2\/pages\/158\/revisions"}],"predecessor-version":[{"id":729,"href":"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-json\/wp\/v2\/pages\/158\/revisions\/729"}],"wp:attachment":[{"href":"http:\/\/ubwp.buffalo.edu\/wnygirahcp\/wp-json\/wp\/v2\/media?parent=158"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}